Does a retrovirally encoded superantigen cause multiple sclerosis?
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منابع مشابه
Does a retrovirally encoded superantigen cause multiple sclerosis?
Retroviruses are commonly associated with neurological disease in animals, for example, inflammatory encephalomyelopathies of sheep (visna virus),' horses (equine infectious anaemia virus), goats (caprine encephalitis/arthritis virus)2 and mice (murine leukaemia virus).3 The first retrovirus shown to be pathogenic in humans was discovered by Gallo's group4 who demonstrated that human lymphotrop...
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It is difficult to think of an aetiological theory that has not been suggested to explain multiple sclerosis. Disconcertingly, however, many of the aetiological questions asked over 150 years ago are still unanswered. Is the disease due to a vascular defect as initially suggested by Rindfleisch in 1863, who noted a blood vessel in the centre of each plaque, or is it a defect in the glial tissue...
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Background: Mesenchymal stem cells (MSCs) with their potential to differentiate into mesodermal and non-mesodermal lineages have several immunomodulatory characteris-tics. These properties make them promising tools in cell and gene therapy. Objective: To evaluate the potential therapeutic applications of autologous MSC in improving clinical manifestations of MS patients. Methods: Ten patients w...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1991
ISSN: 0022-3050
DOI: 10.1136/jnnp.54.10.853